Table 3.
Mixed-Effects Logistic Regression Model on 2-Year Postoperative Complications
| Aliy Complication | Major Complication | Any Infection | Major Infection | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
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| OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | OR | 95% CI | p | |
| Age | 1.02 | 1.01–1.04 | <0.001 | 1.03 | 1.01–1.04 | 0.001 | 1.02 | 1.00–1.04 | 0.070 | 1.00 | 0.98–1.03 | 0.746 |
| BMI | 1.04 | 1.02–1.07 | 0.001 | 1.05 | 1.02–1.07 | 0.001 | 1.06 | 1.03–1.10 | <0.001 | 1.05 | 1.01–1.10 | 0.008 |
| DTI (vs. TE) | 1.34 | 0.81–2.22 | 0.257 | 1.40 | 0.81–2.43 | 0.227 | 1.65 | 0.86–3.18 | 0.133 | 1.67 | 0.77–3.63 | 0.196 |
| Bilateral reconstruction | 1.45 | 1.10–1.91 | 0.008 | 1.52 | 1.11–2.07 | 0.009 | 1.28 | 0.87–1.89 | 0.207 | 1.36 | 0.82–2.26 | 0.238 |
| Prophylactic mastectomy | 0.72 | 0.42–1.22 | 0.219 | 0.84 | 0.47–1.53 | 0.578 | 0.42 | 0.18–0.97 | 0.043 | 0.54 | 0.19–1.50 | 0.236 |
| Mastectomy type | ||||||||||||
| Nipple sparing | Ref. | Ref. | Ref. | Ref. | ||||||||
| Simple/modified radical | 0.73 | 0.50–1.05 | 0.093 | 0.88 | 0.58–1.36 | 0.575 | 0.92 | 0.53–1.61 | 0.768 | 1.04 | 0.51–2.15 | 0.911 |
| ADM used | 1.04 | 0.76–1.40 | 0.823 | 1.19 | 0.85–1.67 | 0.312 | 1.38 | 0.89–2.14 | 0.154 | 1.64 | 0.95–2.82 | 0.076 |
| Lymph node management | ||||||||||||
| None | Ref. | Ref. | Ref. | Ref. | ||||||||
| SLNB | 0.77 | 0.51–1.18 | 0.232 | 0.85 | 0.53–1.37 | 0.507 | 0.68 | 0.39–1.21 | 0.192 | 0.76 | 0.37–1.57 | 0.466 |
| ALND | 0.58 | 0.36–0.95 | 0.030 | 0.71 | 0.41–1.22 | 0.215 | 0.43 | 0.22–0.84 | 0.014 | 0.54 | 0.23–1.24 | 0.144 |
| Diabetes | 0.88 | 0.41–1.88 | 0.748 | 0.94 | 0.41–2.13 | 0.880 | 0.76 | 0.26–2.21 | 0.613 | 0.89 | 0.24–3.29 | 0.855 |
| Smoking status | ||||||||||||
| Nonsmoker | Ref. | Ref. | Ref. | Ref. | ||||||||
| Previous smoker | 1.06 | 0.81–1.39 | 0.677 | 0.99 | 0.73–1.35 | 0.961 | 1.00 | 0.68–1.46 | 0.983 | 0.82 | 0.49–1.38 | 0.454 |
| Current smoker | 2.01 | 0.94–4.29 | 0.072 | 3.25 | 1.50–7.08 | 0.003 | 1.44 | 0.51–4.04 | 0.488 | 1.77 | 0.49–6.33 | 0.382 |
| Radiation | ||||||||||||
| None | Ref. | Ref. | Ref. | Ref. | ||||||||
| Before reconstruction | 1.73 | 1.03–2.92 | 0.039 | 1.83 | 1.03–3.26 | 0.039 | 2.45 | 1.28–4.67 | 0.007 | 3.56 | 1.65–7.68 | 0.001 |
| During/after reconstruction | 2.62 | 1.84–3.73 | <0.001 | 2.86 | 1.95–4.19 | <0.001 | 2.62 | 1.62–4.24 | <0.001 | 3.24 | 1.78–5.90 | <0.001 |
| Chemotherapy during/after reconstruction | 1.25 | 0.93–1.68 | 0.139 | 1.33 | 0.95–1.85 | 0.096 | 1.42 | 0.94–2.14 | 0.100 | 1.35 | 0.79–2.32 | 0.272 |
Ref., reference; DTI, direct-to-implant; TE, tissue expander/implant; BMI, body mass index; ADM, acellular dermal matrix; SLNB, sentinel lymph node biopsy; ALND, axillary lymph node dissection.