Figure 2.

Overview of the number of Leishmania genes with published attempts at the creation of a null mutant. (a) Line graph depicting the cumulative number of genes for which attempts have been made to generate null mutants, for human infective Leishmania species. Only the first attempt at a gene deletion for each individual gene was recorded. Data from this study were ordered by year, and cumulative values of publications per year were derived, where the total number of attempted gene deletions is shown as well as the number of essential genes identified. (b) Pie chart showing the proportion of unique gene deletion attempts by species of Leishmania. Cutaneous species are shaded in yellows, and visceral species, in blues.