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Number of reverse genetic manipulations of Leishmania in comparison to other model parasitic protozoans. (A) Comparison of reverse genetic screening in Leishmania spp. (Table S1), Trypanosoma cruzi (Table S2), Trypanosoma brucei,59Toxoplasma gondii,60 and Plasmodium berghei.67 Pie chart segments depict the proportion of genes in each organism that have been targeted using reverse genetics, with the overall area of the pie depicting the relative sizes of the genomes.
