. 2018 Feb 21;4(4):478–498. doi: 10.1021/acsinfecdis.7b00231

Table 1. Select Chaperone Network Proteins and Their Essentiality for Optimal Growth in Vitro.

protein	E. coli	M. smegmatis	M. tuberculosis
Trigger Factor	nonessential⁵⁴	nonessential⁴⁹	nonessential^a
DnaK	nonessential⁵¹	essential⁴⁹	essential^a
GrpE	nonessential²³³	essential⁴⁹	essential^a
DnaJ	nonessential⁷⁵	DnaJ1 and DnaJ2 collectively essential⁶⁶	DnaJ1 and DnaJ2 essential^a
ClpB	nonessential²³⁴	nonessential⁷²	nonessential⁷²