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. 2018 Apr 16;50:17. doi: 10.1186/s12711-018-0390-1

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Pearson correlation between recombination rate and the ratio of putative deleterious to tolerated alleles for regions that harbour such alleles. Results indicate that regions of low recombination are generally enriched for deleterious variants (R = − 0.26, P = 2.89e−09)