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. 2018 Apr;14(2):207–222. doi: 10.2174/1573405613666170403102235

Table 1.

Denver dissection grading system in blunt blunt cerebrovascular injury and associated stroke rates. A grade I injury heals regardless of therapy. 70% of grade II dissections progress whilst on heparin therapy. Only 8% of pseudoaneurysms (grade III) healed with heparin, about 89% resolves after endovascular stenting. Occluded carotid arteries (grade IV) does not recanalize in the early post-injury period. Grade V injuries (transections) are lethal and refractory to intervention. Stroke risk increases with injury grade.

Grade Type of Dissection Stroke in Carotid Artery Dissection (%) Stroke in Vertebral Artery Dissection (%)
I Luminal irregularity or dissection with <25% luminal narrowing 3 19
II intimal flap or intramural hematoma with luminal narrowing ≥ 25% or intraluminal thrombus 11 40
III Pseudoaneurysm 33 13
IV Total occlusion 44 33
V Transection and free bleeding 100 N/A