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. 2018 Apr 16;18:423. doi: 10.1186/s12885-018-4332-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — MTH1 targeting reduces H23 cell proliferative capacity. WST-1 assay on cells grown in media without transfection reagent (no siRNA), or 5 days after transfection with MTH1 siRNA or scramble siRNA. a H23. b A459. c H522. d MRC-5. (a), (b) and (d) Values from 4 independent experiments were used to generate final mean values and SD. (c) Values from 3 independent experiments were used to generate final mean values and SD. Error bars represent SD. Asterisks indicate a significant difference relative to corresponding no siRNA controls (****P < 0.0001, ***P < 0.001, **P < 0.01, *P < 0.05)