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. 2018 Apr 10;8:111. doi: 10.3389/fcimb.2018.00111

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Copyright © 2018 Spidlova, Stojkova, Dankova, Senitkova, Santic, Pinkas, Philimonenko and Stulik.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Intracellular growth of the FSC200/in dacD mutant strain is affected. (A) Replication inside bone-marrow derived macrophages. FSC200/in dacD mutant strain shows significantly reduced proliferation inside BMMs 24 and 48 h post infection. (B) Replication inside A549 cell line. The significant defect in replication in A549 cell line is visible only at time interval 24 h post infection. At 48 h post infection the replication rate of all strains is the same. **P < 0.01, ***P < 0.001.