Table 3.
Parameter/Group | Control | Vehicle | Low dose (430 mg) | Medium dose (700 mg) | High dose (1480 mg) |
---|---|---|---|---|---|
RBC (1012 /L) | 8.40 ± 0.19a | 9.53 ± 0.17a | 9.45 ± 0.21a | 9.45 ± 0.21a | 9.04 ± 0.46a |
Hb (g/L) | 148.40 ± 4.76a | 165.50 ± 4.96a | 164.50 ± 2.40a | 166.67 ± 2.40a | 160.00 ± 3.58a |
PCV (L/L) | 0.40 ± 0.02a | 0.42 ± 0.02a | 0.43 ± 0.01a | 0.43 ± 0.03a | 0.41 ± 0.01a |
MCV (fL) | 62.20 ± 0.86a | 60.67 ± 1.45a | 60.33 ± 0.76a | 61.00 ± 1.09a | 60.83 ± 0.65a |
MCHC (g/L) | 284.00 ± 0.84a | 286.67 ± 0.67a | 287.50 ± 1.82a | 285.50 ± 0.89a | 290.50 ± 1.06a |
WBC (× 109/L) | 5.86 ± 1.21a | 7.97 ± 1.06a | 6.55 ± 0.78a | 8.00 ± 2.08a | 7.72 ± 1.09a |
Neutrophils (× 109/L) | 0.34 ± 0.09a | 0.78 ± 0.06a | 0.76 ± 0.07a | 0.96 ± 0.05a | 0.98 ± 0.07a |
Lymphocytes (× 109/L) | 4.62 ± 0.07a | 6.51 ± 0.04a | 5.30 ± 0.06a | 6.33 ± 0.03a | 5.96 ± 0.08a |
Monocytes (× 109/L) | 0.25 ± 0.06a | 0.19 ± 0.02a | 0.19 ± 0.02a | 0.32 ± 0.07a | 0.21 ± 0.02a |
Eosinophils (× 109/L) | 0.21 ± 0.06a | 0.17 ± 0.03a | 0.18 ± 0.01a | 0.13 ± 0.08a | 0.15 ± 0.04a |
Basophils (× 109/L) | 0.18 ± 0.05a | 0.19 ± 0.02a | 0.14 ± 0.01a | 0.21 ± 0.07a | 0.14 ± 0.02a |
Icterus index | 2.00 ± 0a | 2.00 ± 0a | 2.00 ± 0a | 2.00 ± 0a | 2.00 ± 0a |
Plasma protein (g/L) | 69.40 ± 1.72a | 73.83 ± 1.47a | 73.33 ± 1.69a | 74.33 ± 2.70a | 75.33 ± 2.35a |
Values in the same row with similar superscript letter were not significantly different (p > 0.05).