Fig. 1.

Cynaroside prevents cisplatin-induced cell death in HK-2 cells. (A) HK-2 cells were treated with cynaroside for various concentration (1.25, 2.5, 5 and 10 μM). Cell viability was measured by MTS assay. Data represent the mean ± SEM of four independent experiments. (B) After pretreatment with 10 μM cynaroside, HK-2 cells were treated with 20 μM cisplatin for 24 hr. HK-2 cells were visualized by tunel assay. Representative images were taken from at least three independent experiments. ^*Means with difference letters are significantly different at p < 0.05 by Duncan’s multiple range test.