Fig. 4.

Cynaroside reduces BUN, Cre and neutrophils in blood on cisplatin animal models. (A–B) Mice were separated 3 group (Control; n = 7, Cisplatin (20mg/kg); n = 7, Cisplatin (20mg/kg) + Cynaroside (10mg/kg); n = 7). Mice were administered with vehicle or cisplatin (20mg/kg). Blood neutrophils were analyzed by IDEXX procyte (A). BUN (B) and Cre (C) in serum are analyzed by FUGI DRI-CHEM 4000i. Data represent the mean ± SEM of three independent experiments. ^*Means with difference letters are significantly different at ^*p < 0.05 vs. cisplatin (20 μM), ^**p < 0.05 vs. control.