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CYP2C19 genotype‐based ontogeny of clearance of omeprazole converted to 5‐hydroxy‐omeprazole. CLOMZ‐M1: Clearance of omeprazole converted to 5‐hydroxy‐omeprazole; EM: extensive metabolizer; UM: ultrarapid metabolizer; IM: intermediate metabolizer; PM: poor metabolizer; PNA: postnatal age. Dashed lines represent the typical ontogeny patterns of clearance of omeprazole converted to 5‐hydroxy‐omeprazole according to CYP2C19 genotype
