Table 2. Surgical and Anesthetic Characteristics of 6 Patients with Angelman Syndrome Undergoing Anesthetic Care.

Patient (No), Age, Weight (kg)	Procedure Duration (min)	Anesthetic Typea	Analgesiab	PACU Duration (min) Disposition
1
7 mo, 7	MLB, EGD, 78	Sevo/Prop	-	68, outpatient
8 mo, 7	MRI, 117	Sevo/Prop	-	47, outpatient
2
2 y, 10	MRI, 111	Sevo/Prop	-	101, outpatient
2 y, 11	Strabismus, 141	Sevo	Fent/APAP	95, outpatient
3 y, 12	T/A, MLB, 93	Sevo	NSAID	44, outpatient
3
7 y, 33	T/A, 58	Sevo	Morphine, LA	32, outpatient
4
16 y, 47	Dental, 90	Mid/Prop/Des	Fent/NSAID, LA	234, outpatient
5
8 y, 33	EGD, 51	Mid/ Sevo/Prop**	-	36, outpatient
8 y, 33	EGD, 35	Mid/ Sevo/Prop**	-	45, outpatient
8 y, 33	EGD, 34	Mid/ Sevo/Prop**	-	22, outpatient
8 y, 31	T/A, EGD, 111	Sevo, Atracuriumc	Fent, LA	36, ICUd
9 y, 31	EGD, 24	Sevo**	-	39, outpatient
20 y, 106	EGD, 34	Sevo/Prop**	-	14, outpatient
6
28 y, 78	LP, 44	Mid/Prop/Iso Succinylcholine	LA	53, ward
28 y, 78	PICC, 65	Mid/Prop††	Fent, LA	43, ward
28 y, 78	CT, 22	Mid/Prop††	-	57, ward
34 y, 89	LP, 77	Mid/Prop/Ket††	Fent, LA	12, ICUe
34 y, 89	CT, 39	Mid/Prop††	-	116, ward

Abbreviations: APAP, acetaminophen; CT, computerized tomography scan; Des, desflurane; EGD, esophagogastroduodenoscopy; Fent, fentanyl; ICU, intensive care unit; Iso, isoflurane; Ket, ketamine; LA, infiltration of procedure site with local anesthetic; LP, lumbar puncture; min , minute; mo, months; MLB, microlaryngoscopy and bronchoscopy; MRI, magnetic resonance imaging scan; Mid, midazolam; NSAID, nonsteroidal antiinflammatory drug; PICC, peripherally inserted central catheter; Prop, propofol; Sevo, sevoflurane; T/A, adenotonsillectomy; y, years.

^aCases were performed under general endotracheal anesthesia unless noted with ** to indicate general mask anesthesia or †† to indicate monitored anesthesia care.

^bNo patient was administered opioid or nonopioid analgesic during Phase I postanesthesia recovery.

^cAtracurium 10 mg was administered with induction, but was not reversed.

^dPlanned ICU admission for postoperative monitoring of airway effort.

^eAdmitted to ICU for treatment of on-going sepsis that was unrelated to procedure.