Table 1.

Characteristics of the Patients

Characteristics	Iceland (n=8,622)	Emory Biobank (n=1,853)	P value*
Age (years)	64.4 (10.7)	65.6 (10.6)	<0.001
Male sex (%)	75.1	73.8	0.24
Diabetes (%)	11.4	31.5	<0.001
Hypertension (%)	54.3	70.7	<0.001
Hyperlipidemia (%)	50.3	74.6	<0.001
Current smoker (%)	27.4	14.7	<0.001
Former smoker (%)	47.6	47.9	0.83
Prior MI (%)	29.7	49.2	<0.001
Prior PCI (%)	4.2	57.5	<0.001
Prior CABG (%)	7.6	31.3	<0.001
Family history (%)	43.1	44.7	0.21
Number of diseased vessels†	1.94 (0.88)	2.10 (0.91)	<0.001
One-vessel disease	39.1	32.0	<0.001
Two-vessel disease	30.3	31.6	0.30
Three-vessel disease	28.1	31.3	0.007
Four-vessel disease	2.5	5.1	<0.001

Data are presented as percentages or means (standard deviation).

MI indicates myocardial infarction; PCI, percutaneous coronary intervention; CABG, coronary artery bypass grafting.

^*P values for continuous variables were calculated using Student’s t-test. P values for categorical variables were calculated using the chi-squared test.

^†Total number of coronary arteries with at least 50% stenosis on coronary angiography (left anterior descending, circumflex, the right and the left main coronary artery).