Table 3.
MICs and FICI of CRE and ampicillin when used either alone or in combination against S. aureus strains.
Strains | MIC | FIC∗∗ | FICI∗∗∗ | ||
---|---|---|---|---|---|
AMP (g/ml) | CRE (mg/ml) | NIS (g/ml) | AMP+ CRE (g/ml + mg/ml) | ||
S. aureus DMST 20651 | 64R | 0.5ND | 16 | 1.0 + 0.125 | 0.27SI |
S. aureus DMST 20652 | 64R | 0.5ND | 16 | 1.0 + 0.125 | 0.27SI |
S. aureus DMST 20653 | 64R | 0.5ND | 16 | 1.0 + 0.125 | 0.27SI |
∗ S. aureus ATCC 29213 | 0.25S | 0.25ND | 0.5 | NT | NT |
∗ S. aureus ATCC 29213 was used as a reference strain; FIC∗∗ was the lowest FIC value; FICI∗∗∗ was the lowest FICI value. SSusceptible; Rresistant; SIsynergistic interaction. NDNo data in CLSI; NT = no test; AMP = ampicillin; CRE = Cyperus rotundus extract; NIS = nisin.