Figure 3.

SIN inhibits MAPKp38 and NF-κB pathway activation in IP rats. (A) The protein levels of p-p38 and p-p65 were detected by Western blot analysis. (B) The expression levels of p38 and p65 phosphorylation are expressed as percent of the control. Saline: rats were injected with 100 μl saline only; Saline+SIN: rats were injected with 30 mg/kg SIN and 100 μl saline; CFA: rats were injected with 100 μl CFA only; CFA+SIN: rats were injected with 30 mg/kg SIN and 100 μl CFA. * p<0.05 vs. Saline group; ^# <0.05 vs. CFA group.