Table 4.
Univariate analysis of prognostic factors for 5-year OS rate in 162 patients with adenocarcinoma of the cecum
| Variable | 5-year OS (%) | p-value | HR (95% CI) |
|---|---|---|---|
| Sex | 0.366 | 1.34 (0.69–2.59) | |
| Male | 59.8 | ||
| Female | 66.7 | ||
| Age (yr) | 0.00 2 | 1.03 (1.01–1.05) | |
| <55 | 69.3 | ||
| ≥55 | 57.3 | ||
| Tumor size (cm) | 0.272 | 1.08 (0.94–1.24) | |
| ≤5 | 58.7 | ||
| >5 | 65.4 | ||
| Tumor stage | <0.001 | 0.15 (0.05–0.39) | |
| T2-3 | 67.2 | ||
| T4 | 17.8 | ||
| Node stage | <0.001 | 0.13 (0.04–0.39) | |
| N0 | 67.1 | ||
| N1-2 | 23.0 | ||
| Dissected LN | 0.267 | 0.97 (0.93–1.01) | |
| ≤9 | 61.6 | ||
| >9 | 62.4 | ||
| Involved node | 0.163 | 1.07 (0.97–1.18) | |
| ≤2 LNs | 64.9 | ||
| >2 LNs | 43.0 | ||
| Disease stage | 0.091 | 2.11 (0.88–5.05) | |
| II | 66.7 | ||
| III | 55.3 | ||
| Tumor grade | 0.607 | 0.84 (0.43–1.61) | |
| I | 65.7 | ||
| II-III | 58.6 | ||
| Surgical margin | 0.065 | 7.68 (0.88–67.16) | |
| Involved | 62.1 | ||
| Free | 75.0 | ||
| Lymphatic-vascular invasion | 0.015 | 2.73 (1.21–6.17) | |
| Present | 44.0 | ||
| Not present | 71.5 | ||
| Perineural invasion | 0.285 | 1.73 (0.63–4.79) | |
| Present | 45.5 | ||
| Not present | 68.1 | ||
| Adjuvant RT | 0.021 | 4.09 (1.80–9.31) | |
| Received | 75.5 | ||
| Not received | 55.8 | ||
| Chemotherapy regimen | 0.409 | 0.78 (0.43–1.40) | |
| Oxaliplatin based | 60.0 | ||
| Others | 65.9 |
OS, overall survival; HR, hazard ratio; CI, confidence interval; LN, lymph node; RT, radiotherapy.