Table 1.
Characteristic | Value or Number of Patients (%) | ||||||
---|---|---|---|---|---|---|---|
| |||||||
All | EBV- Positive |
EBV- Negative |
P Value |
p16- Positive |
p16- Negative |
P Value |
|
Age | |||||||
Median | 51.4 | 47.3 | 56.2 | 52.3 | 59.1 | ||
Range | 16.9–84.8 | 16.9–84.8 | 28.2–77.7 | 16.9–77.7 | 17.2–84.8 | ||
Sex | 0.21 | 0.78 | |||||
Male | 62 (72) | 34 (77) | 22 (63) | 28 (70) | 19 (73) | ||
Female | 24 (28) | 10 (23) | 13 (37) | 12 (30) | 7 (27) | ||
Race | 0.34 | 0.66 | |||||
White | 55 (64) | 30 (68) | 22 (63) | 26 (65) | 16 (62) | ||
African American | 9 (10) | 4 (9) | 3 (9) | 3 (8) | 4 (15) | ||
Asian | 13 (15) | 8 (18) | 4 (11) | 5 (13) | 4 (15) | ||
Hispanic | 9 (10) | 2 (5) | 6 (17) | 6 (15) | 2 (8) | ||
Smoking | 49 (57) | 21 (48) | 24 (69) | 0.10 | 16 (40) | 15 (58) | 0.25 |
WHO Grade | 0.01 | 0.16 | |||||
I | 17 (20) | 4 (9) | 12 (34) | 13 (33) | 4 (15) | ||
II & III | 69 (80) | 40 (91) | 23 (66) | 27 (68) | 22 (85) | ||
T Category | 0.62 | 0.60 | |||||
T1 | 14 (16) | 8 (18) | 4 (11) | 7 (18) | 5 (19) | ||
T2 | 13 (15) | 6 (14) | 7 (20) | 6 (15) | 5 (19) | ||
T3 | 17 (20) | 8 (18) | 9 (26) | 12 (30) | 4 (15) | ||
T4 | 42 (49) | 22 (50) | 15 (43) | 15 (38) | 12 (46) | ||
Nodal Disease | 75 (87) | 41 (93) | 28 (80) | 0.10 | 31 (78) | 26 (100) | 0.01 |
Chemotherapy | 81 (94) | 43 (98) | 31 (89) | 0.16 | 37 (93) | 25 (96) | 0.65 |
Performance Score | |||||||
0–1 | 77 (90) | 41 (93) | 30 (86) | 0.46 | 36 (90) | 25 (96) | 0.64 |
>1 | 9 (10) | 3 (7) | 5 (14) | 4 (10) | 1 (4) |
Abbreviations: EBV, Epstein-Barr virus; WHO, World Health Organization