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. 2018 Apr 11;10:715–734. doi: 10.2147/CMAR.S156837

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© 2018 Guo et al. This work is published and licensed by Dove Medical Press Limited

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Typical processing flow of metabolomics in HCC.

Notes: Proposed standards for metabolomics on HCC are presented in this schematic view. The first step is to collect the samples. Then, the collected samples are preprocessed and tested by different approaches. After acquisition, obtained data are processed and analyzed by multivariate statistical analysis. Lastly, the underlying biological interpretations are elucidated.

Abbreviations: CE, capillary electrophoresis; GC, gas chromatography; HCC, hepatocellular carcinoma; LC, liquid chromatography; MS, mass spectrometry; NMR, nuclear magnetic resonance.