Skip to main content
. 2018 Apr 11;13:1135–1144. doi: 10.2147/COPD.S161257

Figure 2.

Figure 2

Greater release of MMP-9 (A) but lesser release of TIMP-1 (B) by cultured AMs from AHR + S.

Notes: AMs from AHR−NS (n=10), AHR−S (n=13) or AHR+S (n=8) were incubated for 24 hr. The level of MMP-9 (A) and TIMP-1 (B) in the culture supernatants was determined by enzyme-linked immunosorbent assays. The molar ratio between MMP-9 and TIMP-1 was also calculated (C). Values are shown as individual data point, mean, and standard error of mean. *P<0.05 compared to AHR − NS. AHR − NS, nonsmokers without AHR; AHR − S, smokers without AHR; AHR + S, smokers with AHR.

Abbreviations: AHR, airway hyperresponsiveness; AMs, alveolar macrophages; MMP-9, matrix metalloproteinase-9; TIMP-1, tissue inhibitor of metalloproteinase-1.