Table 1.
Comparison of demographic and clinical data between intensive care unit nonsurvivors versus survivors
| Nonsurvivors (n = 27) | Survivors (n = 16) | P value | |
|---|---|---|---|
| Age (years): median (IQR) | 57 (45–67) | 55 (34–63) | 0.22 |
| Male | 20 (69%) | 9 (31%) | 0.31 |
| Body mass index (kg/m2): Median (IQR) | 27 (24–30) | 31 (26–42) | 0.12 |
| Height (cm): Median (IQR) | 170 (162–175) | 173 (163–182) | 0.71 |
| APACHE II: Median (IQR) | 30 (24–33) | 26 (23–26) | 0.03 |
| Reason for ARDS | 0.46 | ||
| Aspiration | 4 (15%) | 3 (19%) | |
| H1N1 | 2 (7%) | 1 (6%) | |
| Pancreatitis | 1 (4%) | 2 (12%) | |
| Pneumonia | 16 (59%) | 10 (62%) | |
| Sepsis | 4 (15%) | 0 (0%) | |
| Mechanical ventilation mode | |||
| Volume control | 15 (56%) | 13 (81%) | 0.11 |
| Pressure control | 9 (33%) | 3 (19%) | 0.48 |
| Airway pressure release ventilation | 2 (7%) | 0 (0%) | 0.52 |
| High-frequency oscillatory ventilation | 1 (4%) | 0 (0%) | 0.99 |
| Tidal volume (mL/kg) during prone: Median (IQR) | 8 (6–8) | 7 (6–8) | 0.55 |
| PEEP during prone (cm H2O): Median (IQR) | 13 (10–15) | 13 (11–15) | 0.87 |
| Plateau during prone (cm H2O) (median/IQR) | 34 (31–40) | 30 (26–35) | 0.02 |
| Driving pressure during prone (cm H2O): Median (IQR) | 22 (14–29) | 17 (15–20) | 0.04 |
| Neuromuscular blocking agents | 26 (96%) | 15 (94%) | 0.99 |
| Corticosteroids | 13 (48%) | 6 (38%) | 0.54 |
| Vasopressors | 17 (63%) | 10 (63%) | 0.99 |
| Inhaled vasodilators | 5 (19%) | 1 (6%) | 0.38 |
| PaO2/FiO2 upon prone: Median (IQR) | 87 (65–132) | 72 (63–115) | 0.17 |
| Time from ARDS diagnosis to prone (h): Median (IQR) | 48 (27–112) | 84 (6–120) | 0.38 |
| Time of first prone (h): Median (IQR) | 25 (9–44) | 40 (20–51) | 0.15 |
| Total time on prone (h): Median (IQR) | 31 (9–62) | 45 (20–87) | 0.39 |
IQR indicates interquartile range (25%–75%); APACHE, Acute Physiology and Chronic Health Evaluation; ARDS, acute respiratory distress syndrome; PEEP, positive end-expiratory pressure; PaO2/FiO2, ratio of arterial pressure of oxygen divided by fraction of inspired oxygen.