Skip to main content
. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Brain Res. 2018 Mar 22;1688:103–112. doi: 10.1016/j.brainres.2018.03.019

Figure 3. Effects of tropicamide on phosphorylation and expression of ERK1/2 in the striatum.

Figure 3

A, Effects of tropicamide on phosphorylation and expression of ERK1/2 in the CPu. B, Effects of tropicamide on phosphorylation and expression of ERK1/2 in the NAc. Representative immunoblots are shown to the left of the quantified data. Note that tropicamide induced a significant increase in pERK2 signals in the CPu (F(1,15) = 7.769, P = 0.014) and NAc (F(1,15) = 6.077, P = 0.026), while the antagonist had no effect on ERK2 expression. Rats were given an i.p. injection of vehicle (Veh) or tropicamide (Tro) at 10 mg/kg and were sacrificed 15 or 30 min after drug injection for Western blot analysis of changes in pERK1/2 and ERK1/2 expression. Data are presented as means ± SEM (n = 4–6 per group). *P < 0.05 versus vehicle at the same time point.