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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2018 Apr;11(4):e005682. doi: 10.1161/CIRCEP.117.005682

Figure 1. Elevated ox-CaMKII increases autonomously activated CaMKII in mdx mice.

Figure 1

(A) Representative Western blots and quantification of total CaMKII expression level in mdx mouse ventricular lysates compared to WT and mdx:MM-VV. (B) Representative Western blots and quantification of oxidation at M281/M282 (ox-CaMKII) demonstrating significantly increased expression of oxidized CaMKII in mdx mouse ventricular lysates compared to WT and mdx:MM-VV. (C) Fold change in total CaMKII activity induced by Ca2+/CaM (top), and Ca2+/CaM-independent CaMKII activity (bottom). *P<0.05, ***P<0.001.