Table 4. The numbers of neovascularization and macrophage infiltrate in the herniated disc (n = 60).
CD34 (+) | p value | CD68 (+) | p value | |
---|---|---|---|---|
Age (years) | ||||
<50 (n = 26) | 13.74 ± 3.87 | 15.48 ± 3.82 | ||
≥50 (n = 34) | 14.52 ± 3.43 | 0.411 | 17.34 ± 3.57 | 0.056 |
Herniation type | ||||
TE (n = 41) | 12.68 ± 3.57 | 16.88 ± 3.72 | ||
S (n = 19) | 14.34 ± 3.28 | 0.102 | 16.16 ± 3.41 | 0.437 |
Disease duration (weeks) | ||||
9–12 (n = 40) | 12.55 ± 3.34 | 15.13 ± 3.83 | ||
13–16 (n = 20) | 14.34 ± 3.96 | 0.071 | 17.16 ± 3.54 | 0.052 |
Modic changes | ||||
+ (n = 23) | 12.74 ± 3.55 | 14.68 ± 3.29 | ||
− (n = 37) | 14.62 ± 3.67 | 0.06 | 16.97 ± 3.97 | 0.019 |
Cartilaginous endplate | ||||
+ (n = 25) | 8.24 ± 3.36 | 9.32 ± 3.29 | ||
− (n = 35) | 16.26 ± 3.67 | < 0.001* | 19.82 ± 3.67 | <0.001* |
mean ± SD.
TE; transligamentous extrusion, S; sequestration.
*Statistically significant (with Bonferroni correction, significance is set at p < 0.005).