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. 2018 Apr 17;13(4):e0195142. doi: 10.1371/journal.pone.0195142

Table 2. KEGG pathways contributing most to the agar-grown phenotype.

KEGG pathways Average P1 SD P1 Average N1 SD N1 Average SR
Regulation of autophagy 1.03E-06 1.69E-06 6.42E-05 9.93E-06 0.02
Sphingolipid metabolism 1.81E-06 8.73E-07 5.20E-05 9.24E-06 0.03
Folate biosynthesis 1.47E-06 5.76E-07 1.80E-05 4.61E-06 0.08
Ubiquitin mediated proteolysis 2.96E-06 6.95E-07 3.11E-05 2.71E-06 0.10
Arachidonic acid metabolism 1.17E-05 3.77E-06 1.15E-04 1.75E-05 0.10
Basal transcription factors 1.74E-06 9.97E-07 1.54E-05 2.86E-06 0.11
ABC transporters 4.39E-06 1.30E-06 3.87E-05 7.76E-06 0.11
Endocytosis 4.73E-06 1.41E-06 2.49E-05 3.41E-06 0.19
SNARE interactions in vesicular transport 3.06E-06 1.86E-06 1.51E-05 2.70E-06 0.20
Sulfur relay system 3.96E-06 1.37E-06 1.95E-05 5.01E-06 0.20

P1: Positive weight of the gene set for constraint 1, N1: Negative weight of the gene set for constraint 1, SR: set ratios (SR = P1/N1) reflecting the contribution of the gene set to the phenotype, SD: standard deviation. See Methods more details about the methodology.