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Crosslinking chemistry of bovine pericardium (BP). a Glutaraldehyde crosslinking mechanism. b Combined crosslinking (TRI) that incorporates EDC + NHS (carbodiimide crosslinking), neomycin, and pentagalloyl glucose (PGG). Inset depicts TRI stabilization of collagen, GAGs, and elastin throughout the entire ECM tissue composite of BP
