Table 1.
CJD and non‐CJD cases evaluated for vCJD prions by hsPMCA
| Diagnosis | Detection of vCJD prions by hsPMCA | |
|---|---|---|
| vCJD | ||
| Definite | 11 (codon 129MM) | 11/11 |
| 1 (codon 129MV) | 1/1 | |
| Possible | 1 (codon 129MM) | 1/1 |
| Probable | 2 (codon 129MM) | 2/2 |
| 15/15 | ||
| sCJD | ||
| Definite | 5 (codon 129MM) | 0/5 |
| Probable | 1 (codon 129MM) | 0/1 |
| 0/6 | ||
| Other neurodegenerative diseasesa | 21 | 0/21 |
| Non‐neurodegenerative diseases and improved cases † | 14 | 0/14 |
a
The ‘other neurodegenerative diseases’ group comprised cases of: Alzheimer's disease, Lewy body disease, Frontotemporal dementia, Cortical/strial/nigral degenerative disorder, Epinocerebellar ataxia, Paraneoplastic syndrome, Voltage gated K channelopathy, and Neuroaxonal dystrophy.
†The ‘other non‐neurodegenerative diseases and improved cases’ group comprise cases of: Diffuse large B cell lymphoma, Carcinomatosis of leptomeninges and brain, Progressive multifocal leukoencephalopathy, Angiotrophic lymphoma, Cerebrovascular disease, Small brain‐stem haemorrhages, Normal pressure hydrocephalus, and Intravascular B cell lymphoma.