Table 3.
Admission clinical features.
| Clinical Features | Total (n = 44)a | Survived (n = 21) | Died (n = 20) | p-value |
|---|---|---|---|---|
| Anorexia | 29/44 | 13/21 | 15/20 | 0.342 |
| Abdominal pain | 28/44 | 13/21 | 15/20 | 0.132 |
| Back pain | 9/44 | 5/21 | 4/20 | 1.0 |
| Conjunctival injection | 10/44 | 5/21 | 5/20 | 1.0 |
| Diarrhoea & vomiting | 33/44 | 13/21 | 19/20 | 0.006 |
| Dyspnoea | 7/44 | 2/21 | 5/20 | 0.217 |
| Delirium/encephalopathy | 11/44 | 2/21 | 9/20 | 0.012 |
| Fever | 27/44 | 14/21 | 11/20 | 0.539 |
| Haemorrhage | 3/44 | 2/21 | 1/20 | 0.583 |
| Headache | 25/44 | 13/21 | 10/20 | 0.543 |
| Hiccups | 10/44 | 2/21 | 8/20 | 0.027 |
| Lethargy/malaise | 31/44 | 12/21 | 17/20 | 0.096 |
| Myalgia | 25/44 | 11/21 | 12/20 | 0.766 |
| Arthralgia | 19/44 | 10/21 | 7/20 | 0.372 |
| Nausea | 23/44 | 9/21 | 13/20 | 0.143 |
| Vital signs at admission | ||||
| Pulse – mean (SD) | 90.6 (16.9) | 89.2 (19) | 92 (16) | 0.58 |
| Systolic BP – mean (SD) | 125 (21.3) | 118 (19) | 134 (21) | 0.02 |
| Temperature – median (range) | 37.3 (36.1–39.6) | 37.2 (36.1–39.6) | 37.4 (36.3–39.2) | 0.354 |
| Respiratory rate – median (range) | 22 (14–44) | 23 (17–44) | 22 (14–42) | 0.217 |
| Saturations – median (range) | 97 (83–99) | 96 (83–99) | 98 (91–99) | 0.02 |
| EVD stage at admission | ||||
| Stage 1 | 9/44 | 6/21 | 1/20 | |
| Stage 2 | 12/44 | 8/21 | 3/20 | |
| Stage 3 | 23/44 | 7/21 | 16/20 | 0.009 |
| Highest EVD stage during admission | ||||
| Stage 1 | 1/41 | 1/21 | 0/20 | |
| Stage 2 | 8/41 | 8/21 | 0/20 | 0.004 |
| Stage 3 | 32/41 | 12/21 | 20/20 | |
| NEWS score at admission Mean (SD) |
4.1 (3.5) | 3 (1.9) | 5.5 (4.4) | 0.02 |
| qSOFA score at admission Median (range) |
1 (0–3) | 1 (0–2) | 1 (0–3) | 0.359 |
| Ct value at admission (n = 42) Median |
20.7 (14.3–37.2) | 23.4 (16.2–37.2) | 19.6 (14.3–32.1) | 0.001 |
a
44 patients with confirmed EVD were managed at the EVD treatment unit, with 41 admitted until discharge/death. 3 patients were aeromedically evacuated to the USA/Europe. (SD – standard deviation, BP – blood pressure, qSOFA – quick Sepsis Related Organ Failure Assessment, Ct – cycle threshold).