Table 3.
Demographics, baseline, and outcomes data for patients with admission INR (n=459)
| DEMOGRAPHICS | CC+ (n=18, 4%) | CC− (n=441, 96%) | p |
|---|---|---|---|
|
| |||
| Age (years) | 59 (27, 77) | 43 (26, 57) | 0.05 |
|
| |||
| Male (n, %) | 13 (72%) | 318 (72%) | 0.99 |
|
| |||
| Injury type (n, %) | 0.45 | ||
| Blunt only | 13 (72%) | 365 (83%) | |
| Penetrating only | 4 (22%) | 66 (15%) | |
| Both | 1 (6%) | 10 (2%) | |
|
| |||
| ISS | 30 (19, 38) | 20 (10, 29) | <0.01 |
|
| |||
| PREHOSPITAL FLUIDS | |||
|
| |||
| Crystalloid infusion (ml) | 325 (100, 700) | 600 (250, 1100) | 0.07 |
|
| |||
| Transfused prehospital RBCs (n, %) | 7 (39%) | 28 (6%) | <0.001 |
|
| |||
| Transfused prehospital plasma (n, %) | 8 (44%) | 34 (8%) | <0.001 |
|
| |||
| ED | |||
|
| |||
| Systolic blood pressure (mm Hg) | 120 (84, 148) | 130 (109, 148) | 0.30 |
|
| |||
| Heart rate (bpm) | 101 (79, 125) | 99 (81, 115) | 0.84 |
|
| |||
| pH | 7.31 (7.19, 7.35) | 7.31 (7.24, 7.37) | 0.32 |
|
| |||
| Base excess (mEq/L) | −4 (−7.5, −3) | −3.5 (−6.6, −1.3) | 0.36 |
|
| |||
| Hemoglobin (g/dL) | 11.6 (9.9, 12.8) | 13 (11.6, 14.3) | 0.03 |
|
| |||
| Platelet count (x 109/L) | 198 (150, 321) | 223 (181, 269) | 0.83 |
|
| |||
| INR | 1.1 (1.0, 1.3) | 1.4 (1.1, 2.0) | <0.01 |
|
| |||
| INR > 1.5 | 8 (44%) | 51 (12%) | <0.001 |
|
| |||
| Emergent (≤90 minutes) OR or IR (n, %) | 11 (61%) | 75 (17%) | <0.001 |
|
| |||
| OUTCOMES | |||
|
| |||
| Total blood products at 4 hours (units) | 15 (4, 30) | 0 (0, 3) | <0.001 |
|
| |||
| Total blood products at 24 hours (units) | 17 (4, 45) | 0 (0, 5) | <0.001 |
|
| |||
| Death at 4 hours (n, %) | 0 (0%) | 5 (1%) | 0.65 |
|
| |||
| Death at 24 hours (n, %) | 1 (6%) | 25 (6%) | 0.98 |
|
| |||
| Death at 30 days (n, %) | 5 (28%) | 51 (12%) | 0.06 |
|
| |||
| Primary cause of death | |||
|
| |||
| Exsanguination (n, %) | 1 (6%) | 5 (1%) | 0.21 |
|
| |||
| TBI (n, %) | 4 (22%) | 35 (8%) | 0.06 |
|
| |||
| Sepsis/MOF (n, %) | 0 (0%) | 5 (1%) | 1.00 |
|
| |||
| Other/Unknown (n, %) | 0 (0%) | 6 (1%) | 1.00 |