Table 4.
Gestational day 35 fetal retrievals from somatic cell nuclear transfer of CPI (100 μM CPI-613) and PS48 (10 μM) treated GFP (green fluorescent protein) and TOM (tomato fluorescent protein) fibroblasts.
| Gilt recipient cycle day | Blastocysts transferred | Developmental day of blastocysts | Total litter size | Number of CPI fetuses‡ | Number of PS48 fetuses‡ |
|---|---|---|---|---|---|
| 5 | 50 | 6 | 7 | 2 TOM | 5 GFP |
| 4 | 40 | 6 | 1* | 1 GFP | None |
| 4 | 40 | 6 | 5 | 5 GFP | None |
| 5 | 50 | 6 | 2 | 1 GFP | 1 TOM |
| 4 | 46 | 6 | 13 | 5 TOM | 8 GFP |
‡
Donor fibroblasts treated for 7 days with the pharmaceuticals CPI (100 μM) or PS48 (10 μM) prior to somatic cell nuclear transfer.
*
Uterus contained 3 small regressing fetuses with no observable fluorescence.