Table 5.
Impact of 7 day donor cell treatment with 100 μM CPI-613 or 10 μM PS48 treated GFP (green fluorescent protein) and TOM (tomato fluorescent protein) fibroblasts on clone embryo transfer survival to day 35 of gestation.
Treatment‡ | Cell line | Survival probability≠ | SE | P-value |
---|---|---|---|---|
CPI | GFP | 0.066 | 0.023 | 0.05 |
PS48 | GFP | 0.105 | 0.021 | |
CPI | TOM | 0.057 | 0.021 | |
PS48 | TOM | 0.094 | 0.023 |
Donor fibroblasts treated for 7 days with the pharmaceuticals CPI (100 μM) or PS48 (10 μM) prior to somatic cell nuclear transfer.
Survival probability: number of piglets collected at day 35 of gestation from total number of reconstructed embryos transferred.