Table 7.
Interaction of 7 day donor cell treatment with MIX (100 μM CPI-613 and 10 μM PS48) or CON (0 μM) on GFP (green fluorescent protein) or TOM (tomato fluorescent protein) fibroblasts on clone embryo transfer survival to day 35 of gestation.
| Treatment‡ | Cell line | Survival probability≠ | SE | P-value |
|---|---|---|---|---|
| CON | GFP | 0.070 | 0.019 | 0.60 |
| MIX | GFP | 0.077 | 0.017 | |
| CON | TOM | 0.020 | 0.017 | |
| MIX | TOM | 0.009 | 0.019 |
Donor fibroblasts treated for 7 days with the pharmaceuticals CPI (100 μM) and PS48 (10 μM) or as CON (0 μM) prior to somatic cell nuclear transfer.
Survival probability: number of piglets collected at day 35 of gestation from total number of reconstructed embryos transferred.