Table 2. The efficacy of standard triple therapy with different durations of administration .
Year | City | Therapy |
Treatment duration
(days) |
Number of
patients. |
Underlying disease | Eradication assessment method. |
Duration from therapy
(week) |
Per-protocol eradication rate |
2003 | Ardabi24 | OAC | 7 | 45 | Gastritis | UBT | 8 | 42 |
2006 | Tehran25 | OAC | 7 | 120 | H. pylori (+) | UBT | 6 | 91.8 |
2012 | Kerman26 | OPC | 7 | 34 | H. pylori (+) | ? | ? | 73 |
2010 | Rasht27 | OAC | 10 | 107 | NUD | Stool Antigen | 8 | 90.7 |
2010 | Tehran28 | OAC | 10 | 104 | PUD | UBT | 8 | 90.4 |
2013 | Ghom29 | OAC | 10 | 76 | H. pylori (+) | UBT | 6 | 83 |
2013 | Ahvaz30 |
OAC LAC EAC |
10 |
98 97 98 |
H. pylori (+) | UBT | 6 |
91.9 80.4 91.8 |
2015 | Ahvaz31 | OAC | 10 | 100 | H. pylori (+) | UBT | 8 | 93.9 |
2007 | Kermashah32 |
OAC (C: half dose) OAC |
14 14 |
53 53 |
H. pylori (+) | UBT | 6 |
88 89 |
2009 | Yazd35 | OAC | 14 | 53 | H. pylori (+) | UBT | 4 - 6 | 70 |
2013 | Shiraz34 |
OAC OPC |
14 |
110 110 |
PUD | UBT | 6 |
90.8 87 |
2014 | Tehran33 | OAC | 14 | 39 | GU | Biopsy | 8 | 82.9 |
2015 | Tehran36 |
OAC OAC |
14 14 (A:28) |
33 33 |
H. pylori (+) | Stool Antigen | 4 |
63.6 90.9 |
O: Omeprazole, L: Lansoprazole, P: Pantoprazole, E: Esomeprazole, Amox: Amoxicillin, Cla: Clarithromycin, GU: Gastric ulcer, PUD: Peptic ulcer disease, NUD: Non-ulcer dyspepsia,
UBT: Urea breath test