Table 3.
Baseline properties of C-fibers (mean ± SD).
| Group | Von Frey threshold (mbars) | Heat threshold (°C)1 | Cold threshold (°C)2 | Mechanical threshold (g) | Conduction Velocity (m/s)3 |
|---|---|---|---|---|---|
| No vector and hsvCON (n =34) | 1.8 ± 0.6 | 40.1 ± 4.5 | 14.0 ± 6.4 | 1.8 ± 0.8 | 0.65 ± 0.2 |
| hsvMOR (n = 18) | 1.4 ± 0.8 | 38.2 ± 5.9 | 12.9 ± 6.4 | 1.9 ± 1.7 | 0.74 ± 0.25 |
| SNL no vector and hsvCON (n = 43) | 1.5 ± 0.7 | 41.2 ± 3.9* | 17.3 ± 9.8† | 3.0 ± 2.3 | 0.65 ± 0.26‡ |
| SNL hsvMOR (n = 16) | 1.6 ± 0.4 | 41.8 ± 5.6* | 17.2 ± 6.0† | 1.6 ± 0.5 | 0.48 ± 0.08‡ |
SNL, spinal nerve ligation.
1
Significant increase in SNL (SNL no vector and hsvCON; SNL hsvMOR) vs. uninjured fibers (no vector and hsvCON; hsvMOR).
*
ANOVA: F(1, 74) = 5.7, P<0.01
2
Significant decrease in SNL (SNL no vector and hsvCON; SNL hsvMOR) vs. uninjured fibers (no vector and hsvCON; hsvMOR).
†
ANOVA: F(1, 64) = 6.2, P<0.01.
3
Significant decrease in SNL (SNL no vector and hsvCON; SNL hsvMOR) vs. uninjured fibers (no vector + hsvCON and hsvMOR).
‡
ANOVA: F(1, 107) = 6.4, P<0.05.
1 Millibar (mbar) = 0.0001 mN force.