Table 3.
Rabies antibody titers for vaccine-naïve dogs with pre-vaccination RFFIT titer >0.05 IU/mL and matched controls (pre-vaccination RFFIT <0.05 IU/mL), before and after primary rabies vaccination
| Pre-Rabies Vaccination | Post-Rabies Vaccination | ||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Groupa | RFFIT Titer | IU/mL | RFFIT Interpretation | ELISAb | ELISA Interpretation | RFFIT Titer | IU/mL | Interpretation | |
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| Pre-Vaccination rVNA | PI | 1:25 | 0.18 | Positive | 38% | Negative | 1:1400 | 10 | Positive |
| PE | 1:56 | 0.45 | Positive | 99% | Positive | 1:1300 | 10 | Positive | |
| PP | 1:33 | 0.24 | Positive | 88% | Positive | 1:200 | 1.5 | Positive | |
| PP | 1:7 | 0.052 | Positive | 78% | Positive | 1:250 | 1.8 | Positive | |
| PI | 1:180 | 1.3 | Positive | 75% | Positive | 1:22652 | 170 | Positive | |
| O | 1:29 | 0.21 | Positive | 13% | Negative | 1:1100 | 8.1 | Positive | |
| PI | 1:7 | 0.052 | Positive | 10% | Negative | 1:1400 | 10 | Positive | |
| O | 1:250 | 1.8 | Positive | 89% | Positive | 1:65 | 0.48 | Positive | |
| PE | 1:11 | 0.081 | Positive | 80% | Positive | 1:270 | 2 | Positive | |
| PI | 1:54 | 0.43 | Positive | 77% | Positive | Not available for follow-up | |||
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| Controls | O | <1:5 | <0.04 | Negative | 11% | Negative | 1:900 | 6.7 | Positive |
| O | <1:5 | <0.04 | Negative | 1% | Negative | <1:5 | <0.04 | Negative | |
| O | <1:5 | <0.04 | Negative | 12% | Negative | <1:5 | <0.04 | Negative | |
| PE | <1:5 | <0.04 | Negative | −8% | Negative | 1:85 | 0.63 | Positive | |
| PE | <1:5 | <0.04 | Negative | 20% | Negative | 1:3125 | 23 | Positive | |
| PP | <1:5 | <0.04 | Negative | 3% | Negative | 1:50 | 0.36 | Positive | |
| PP | <1:5 | <0.04 | Negative | −7% | Negative | 1:625 | 4.6 | Positive | |
| PP | <1:5 | <0.04 | Negative | −17% | Negative | 1:1000 | 7.4 | Positive | |
| PP | <1:5 | <0.04 | Negative | −2% | Negative | 1:1300 | 9.6 | Positive | |
| PI | <1:5 | <0.04 | Negative | 8% | Negative | 1:95 | 0.7 | Positive | |
Vaccine received: PI, parenteral improperly-stored; PE, parenteral expired; PP, parenteral properly-stored; O, oral.
ELISA values represent percent blocking (positive >40% blocking).