Table 2.
Clinical manifestations of Carney Complex in previous reports
| Carney [4])/1985 n=40 |
Stratakis [3]/2001 n=338 |
Correa [5]/2015 n=750 |
|
|---|---|---|---|
| Gender | |||
| Male | 40 | 43 | 37 |
| Female | 60 | 57 | 63 |
| Family history | 25 | 70 | 70 |
| Clinical manifestations | |||
| Spotty skin pigmentation | 65 | 77 | 70-80 |
| Cardiac myxoma | 72 | 53 | 20-40 |
| Cutaneous myxoma | 45 | 33 | 30-50 |
| Primary pigmented nodular adrenocortical disease (PPNAD) | 45 | 26 | 25-60 |
| Large-cell calcifying Sertoli cell tumor or steroid-type tumor or both | 56 | 33 | 41 |
| Mammary myxomatosis or fibroadenoma | 42 | 3 | 20 |
| Pituitary adenoma (acromegaly) | 10 | 10 | 75 |
| Thyroid tumors | 0 | 5 | 75 |
| Osteochondromyxoma | 0 | 2 | rare |
| Psammomatous melanotic schwannoma | 5 | 10 | 10 |
| Blue nevus | 0 | 0 | 75 |
| Mutation of PRKAR1A gene | NA | 41 | 70-80 |
The table gives the percentage of CNC patients
NA not available