Table 4.

Clinical characteristics of the 5 Carney Complex patients with thyroid lesion reported in Japan

No.	Author/Year/Ref. no.	Age(y)/Sex	Family history	Carney complex manifestations	PRKAR1A mutation
1	Ando et al./2015/ [9]	72/F	no	Thyroid tumor, lentigines, pituitary adenoma (TSH-producing tumor)	NA
2	Okamoto et al./2017/ [8]	73/F	no	Thyroid tumor, lentigines, pituitary adenoma (TSH-producing tumor)	none
3	Kako et al./1999/ [11]	47/F	no	Thyroid tumor, lentigines, cardiac myxoma, PPNAD	NA
4	Yamashita et al./2015/ [10]	20/F	no	Thyroid tumor, breast myxoma, cardiac myxoma, PPNAD, acromegaly	NA
5	Our case/2017	69/F	no	Thyroid tumor, cardiac myxoma	none

TSH thyroid stimulating hormone; PPNAD primary pigmented nodular adrenocortical disease; NA not available