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. 2018 Apr 17;9:1513. doi: 10.1038/s41467-018-03986-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 10 — Relationship between parasitism and PI3Kγ expression in the heart tissue of CCC patients. a Quantitative real-time PCR analysis of T. cruzi DNA levels (pg/50 ng of human DNA) in heart tissue from CCC patients. The black line indicates the lowest amount of parasite detected by reaction. b qRT-PCR analysis of the mRNA expression of PIK3CG in the heart tissue of CCC patients segregated by high (n = 5) or low (n = 6) heart parasitism. Unpaired Student’s t-test in b. Data are from one experiment (mean ± s.e.m in b)