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. 2018 Apr 18;8:85. doi: 10.1038/s41398-018-0132-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Sample traces of sEPSCs from WT (blue trace) and Df(16)A^+/− (red trace) neurons at DIV7 (upper panel) and DIV14 (lower panel), respectively. Scale bar as shown in inset. b Sample traces of mEPSCs from WT (blue trace) and Df(16)A^+/− (red trace) neurons at DIV7 (upper panel) and DIV14 (lower panel), respectively. Scale bar as shown in inset. c Bar graphs of sEPSCs of WT and Df(16)A^+/− cortical neurons at DIV7 and DIV14. No significant difference was observed between genotypes. d Bar graphs of mEPSCs of WT and Df(16)A^+/− cortical neurons at DIV7 and DIV14. No significant difference was observed between genotypes. e Sample traces of sIPSCs from WT (blue trace) and Df(16)A^+/− (red trace) neurons at DIV7 (upper panel) and DIV14 (lower panel), respectively. Scale bar as shown in inset. f Sample traces of mIPSCs from WT (blue trace) and Df(16)A^+/− (red trace) neurons at DIV7 (upper panel) and DIV14 (lower panel), respectively. Scale bar as shown in inset. g Bar graphs of sIPSCs of WT and Df(16)A^+/− cortical neurons at DIV7 and DIV14. Df(16)A^+/− cortical neurons showed significant increase in frequency at DIV7 compared to WT neurons (t test, *p < 0.05). h Bar graphs of mIPSCs of WT and Df(16)A^+/− cortical neurons at DIV7 and DIV14. Df(16)A^+/− cortical neurons showed significant increase in amplitude at DIV14 compared to WT neurons (t test, *p < 0.05)