Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Apr 18;8:85. doi: 10.1038/s41398-018-0132-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — a Graph shows voltage-gated calcium responses in WT (open circles) and Df(16)A^+/− (closed circles) cortical neurons at DIV7 by exposing to 30 mM KCl for 2 s (top panel), 5 s (middle panel), and 10 s (bottom panel). b Graph shows voltage-gated calcium responses in WT (open circles) and Df(16)A^+/− (closed circles) cortical neurons at DIV14 by exposing to 30 mM KCl for 2 s (top panel), 5 s (middle panel), and 10 s (bottom panel). Neurons were loaded with Fura-2. Data were plotted as the ratio of fluorescence intensity excited at 340 and 380 nm vs. time and the values were normalized to the averaged baseline level. c Summary data of calcium imaging for WT and Df(16)A^+/− cortical neurons at DIV7. Compared to WT neurons, Df(16)A^+/− neuros showed significantly lower peak value of calcium elevation at 2 s and smaller AUC under all treatments. d Summary data of calcium imaging for WT and Df(16)A^+/− cortical neurons at DIV14. Significantly decreased basal calcium level, lower peak values, smaller AUC, and faster recovery were observed for Df(16)A^+/− neurons compared to WT ones