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. 2018 Apr 18;8:85. doi: 10.1038/s41398-018-0132-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a PCA analysis indicates a good separation of the expression profiles between WT (green) and Df(16)A^+/− (red) cortical neurons at DIV7. b Volcano plot indicating downregulation of the genes within the 22q11.2 deletion region and upregulation of primary miRNA genes and Mirta22/Emc10 as previous reported. c GO and phenotype analysis of significantly upregulated genes (FDR adjusted p < 0.05). d GO and phenotype analysis of significantly downregulated genes (FDR adjusted p < 0.05)