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. 2018 Feb 19;135(5):743–755. doi: 10.1007/s00401-018-1825-z

Table 1.

Overview of TCGA, French GWAS and French seq series and mutation status of tumours

Dataset Controls Cases (GBM/non-GBM) Case groupings
IDH status EGFR CDKN2A Molecular subgroup WHO 2016 classification
mut wt amp wt del wt IDH-only TERT-IDH TERT-only Triple −ve Triple +ve Total AstroIDH-mut Astro IDH-wt Oligo 1p19q GBM IDH-mut GBM IDH-wt Total
TCGA 2648 521 (183/338) 293 228 246 270 254 262 100 4 45 10 65 224 166 51 116 10 171 514
French GWAS 1190 1423 (430/993) 366 498 118 628 173 573 169 46 309 141 85 750 188 214 95 27 233 757
French seq 5527 704 (181/523) 427 277 101 592 144 549 181 28 185 92 199 685 178 114 218 31 148 689
Total 9365 2648 (795/1854) 1086 1003 465 1490 571 1384 450 78 539 243 349 1659 532 379 429 68 552 1960

Amp amplified, astro astrocytoma, del deleted, mut mutated, oligo oligodendroglioma, wt wildtype