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. Author manuscript; available in PMC: 2018 Apr 18.
Published in final edited form as: Int J Hematol. 2017 Jun 19;106(3):335–344. doi: 10.1007/s12185-017-2283-4

Fig. 2.

Fig. 2

Schematic of the canonical FA pathway. FA genes can be organized by their relationship to FANCI/D2 monoubiquitination. The most recently identified FA genes (discussed in this review) are bolded in red. Because FANCV/REV7 has multiple activities, whether its polymerase function is the most relevant to FA is unclear