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. 2018 Apr 11;11:121. doi: 10.3389/fnmol.2018.00121

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Copyright © 2018 Zhou, Lv, Wang, Zhang, Chen and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GLYX-13 did not attenuate the NR2B siRNA-induced impairments in PPI of mice. (A) NR2B siRNA significantly increased the startle amplitude. (B) Effect of GLYX-13 on PPI inhibition induced by NR2B siRNA in mice. Data represent the mean ± SEM (n = 12 per group; ^∗P < 0.05, ^∗∗P < 0.01, and ^∗∗∗P < 0.001, versus the NC siRNA + vehicle-treated group).