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GLYX-13 did not reverse the downregulation of DISC1 induced by NR2B siRNA in mice. (A,B) Representative images of immunoblots using antibodies against NR2B and DISC1 along with quantitative analyses. Data are expressed as the mean ± SEM (n = 4 per group for western blotting; ∗∗P < 0.01 and ∗∗∗P < 0.001 compared with the NC siRNA + vehicle-treated group).
