Table 1. Neuropsychological Status of HIV-IC and HAND.
HIV-IC (n = 12) | HAND (n = 10) | P | |
---|---|---|---|
Speed of information processing (preserved/impaired) | 12/0 | 9/1 | 0.455 |
K-WAIS digit symbol subtest, ASS† | 13.3 ± 0.4 | 12.5 ± 0.7 | 0.628 |
TMT A, s | 27.5 ± 2.4 | 39.6 ± 4.5 | 0.032* |
Memory including learning and recall (preserved/impaired) | 12/0 | 5/5 | 0.010* |
K-AVLT delayed recall, ASS | 11.8 ± 0.6 | 7.9 ± 1.2 | 0.008* |
K-AVLT delayed recognition, ASS | 11.8 ± 0.8 | 9.7 ± 1.0 | 0.117 |
K-AVLT total (Trial 1–5), SS† | 60.5 ± 6.9 | 47.8 ± 10.8 | 0.006* |
KCFT copy, ASS† | 15.5 ± 0.6 | 15.4 ± 0.7 | 1.000 |
KCFT immediate recall, ASS | 14.6 ± 0.7 | 13.1 ± 1.1 | 0.251 |
KCFT delayed recall, ASS | 14.3 ± 0.8 | 13.2 ± 1.1 | 0.406 |
Abstraction or executive function (preserved/impaired) | 11/1 | 2/8 | 0.002* |
WCST percent conceptual level responses, SS | 103 ± 4.8 | 82.6 ± 4.6 | 0.006* |
WCST perseverative errors, SS† | 106.8 ± 5.7 | 87.8 ± 4.1 | 0.080 |
WCST total number of errors, SS | 103.8 ± 4.8 | 81.8 ± 5.1 | 0.005* |
K-WAIS similarity subtest, ASS | 12.7 ± 0.6 | 12.2 ± 0.8 | 0.628 |
TMT B, s† | 88.3 ± 12.2 | 189.7 ± 44.1 | 0.030* |
Attention or working memory (preserved/impaired) | 12/0 | 12/0 | N/A |
K-WAIS digits span subtest, ASS | 13.7 ± 0.8 | 11.9 ± 0.9 | 0.165 |
Sensory Perception or motor skills (preserved/impaired) | 10/2 | 2/8 | 0.008* |
Grooved Pegboard Test, s† | 63.7 ± 3.1 | 87.7 ± 9.2 | 0.003* |
Verbal or language (preserved/impaired) | 12/0 | 1/9 | 0.455 |
K-WAIS vocabulary subtest† | 11.9 ± 0.6 | 11.3 ± 0.9 | 0.346 |
Data are mean values ± standard deviation. *p < 0.05, †Tested using nonparametric method. ASS = age-scaled scores, HAND = HIV-associated neurocognitive disorders, HIV = human immunodeficiency virus, HIV-IC = HIV-infected patients with intact cognition, K-AVLT = Korean version of Auditory Verbal Learning Test, KCFT = age-corrected scores on Korean complex figure test, K-WAIS = Korean version of Wechsler Adult Intelligence Scale, N/A = not applicable, s = seconds, SS = standard scores, TMT A = trail making test part A, TMT B = trail making test part B, WCST = Wisconsin Card Sorting Test