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. 2018 Apr 6;19(3):431–442. doi: 10.3348/kjr.2018.19.3.431

Table 2. Comparison of Mean DTI Values between Groups in ROI-Based Analysis.

Mean DTI Values in ROI HAND (n = 10) HIV-IC (n = 12) HC (n = 11) Pa Post-Hoc Analysis
P1b P2c P3d
FA
 CST_R 0.42830 ± 0.02436 0.44567 ± 0.02428 0.48042 ± 0.02233 < 0.001* 0.290 < 0.001** 0.004**
 SLF_R 0.33062 ± 0.03027 0.37167 ± 0.02961 0.39266 ± 0.02821 < 0.001* 0.008** < 0.001** 0.291
 SLFTP_R 0.31225 ± 0.03759 0.33253 ± 0.01996 0.35941 ± 0.03130 0.004* 0.372 0.003** 0.119
MD
 ATR_L 0.00049 ± 0.00003 0.00047 ± 0.00002 0.00045 ± 0.00001 0.001* 0.148 < 0.001** 0.067
 ATR_R 0.00048 ± 0.00003 0.00047 ± 0.00002 0.00044 ± 0.00001 < 0.001* 0.614 < 0.001** 0.005**
 CCG_L 0.00054 ± 0.00003 0.00053 ± 0.00003 0.00050 ± 0.00003 0.009* 1.000 0.010** 0.075
 CCG_R 0.00050 ± 0.00006 0.00050 ± 0.00004 0.00046 ± 0.00003 0.049* 1.000 0.091 0.109
 CST_L 0.00047 ± 0.00002 0.00045 ± 0.00001 0.00043 ± 0.00001 < 0.001* 0.139 < 0.001** 0.008**
 CST_R 0.00046 ± 0.00002 0.00045 ± 0.00001 0.00043 ± 0.00001 < 0.001* 0.695 < 0.001** 0.003**
 FCPM† 0.00055 ± 0.00005 0.00054 ± 0.00003 0.00052 ± 0.00003 0.041* 0.974 0.024 0.037
 FCPm 0.00050 ± 0.00004 0.00049 ± 0.00003 0.00047 ± 0.00001 0.113 NA NA NA
 IFOF_L† 0.00056 ± 0.00004 0.00054 ± 0.00002 0.00051 ± 0.00002 0.002* 0.203 0.001** 0.004**
 IFOF_R 0.00054 ± 0.00003 0.00053 ± 0.00002 0.00050 ± 0.00002 0.001* 0.419 0.001** 0.042**
 ILF_L† 0.00053 ± 0.00004 0.00051 ± 0.00002 0.00049 ± 0.00002 0.001* 0.228 < 0.001** 0.007**
 ILF_R 0.00053 ± 0.00003 0.00053 ± 0.00002 0.00050 ± 0.00002 0.001* 0.931 0.001** 0.012**
 SLF_L† 0.00053 ± 0.00003 0.00051 ± 0.00003 0.00049 ± 0.00002 0.001* 0.021 < 0.001** 0.069
 SLF_R† 0.00053 ± 0.00003 0.00050 ± 0.00003 0.00048 ± 0.00002 0.002* 0.069 < 0.001** 0.051
 SLFTP_L 0.00053 ± 0.00003 0.00051 ± 0.00002 0.00049 ± 0.00002 0.001* 0.058 < 0.001** 0.129
 SLFTP_R 0.00052 ± 0.00003 0.00050 ± 0.00002 0.00048 ± 0.00002 0.001* 0.194 0.001** 0.065
 UF_L 0.00061 ± 0.00004 0.00061 ± 0.00003 0.00056 ± 0.00004 0.005* 1.000 0.030** 0.006**
RD
 ATR_L 0.00041 ± 0.00003 0.00039 ± 0.00002 0.00037 ± 0.00001 0.002* 0.194 0.002** 0.128
 ATR_R 0.00040 ± 0.00003 0.00038 ± 0.00002 0.00036 ± 0.00001 0.001* 0.305 0.001** 0.038**
 CCG_L† 0.00044 ± 0.00004 0.00043 ± 0.00003 0.00040 ± 0.00003 0.014* 0.497 0.002** 0.059
 CCG_R 0.00047 ± 0.00006 0.00045 ± 0.00004 0.00041 ± 0.00005 0.026* 1.000 0.032** 0.112
 Ch_R 0.00043 ± 0.00004 0.00040 ± 0.00004 0.00039 ± 0.00003 0.131 NA NA NA
 CST_L 0.00035 ± 0.00002 0.00033 ± 0.00002 0.00031 ± 0.00001 < 0.001* 0.151 < 0.001** 0.025**
 CST_R 0.00034 ± 0.00002 0.00033 ± 0.00002 0.00030 ± 0.00001 < 0.001* 0.171 < 0.001** 0.006**
 FCPM 0.00038 ± 0.00004 0.00036 ± 0.00002 0.00034 ± 0.00002 0.010* 0.235 0.008** 0.386
 FCPm 0.00041 ± 0.00003 0.00039 ± 0.00003 0.00037 ± 0.00002 0.027* 0.722 0.025** 0.281
 IFOF_L† 0.00043 ± 0.00003 0.00041 ± 0.00003 0.00039 ± 0.00002 0.006* 0.254 0.001** 0.044
 IFOF_R 0.00043 ± 0.00003 0.00042 ± 0.00002 0.00039 ± 0.00002 0.004* 0.402 0.003** 0.101
 ILF_L 0.00042 ± 0.00004 0.00039 ± 0.00002 0.00037 ± 0.00002 0.003* 0.127 0.002** 0.276
 ILF_R 0.00044 ± 0.00003 0.00043 ± 0.00002 0.00040 ± 0.00002 0.002* 0.554 0.002** 0.039**
 SLF_L 0.00043 ± 0.00004 0.00040 ± 0.00003 0.00038 ± 0.00002 0.003* 0.059 0.001** 0.069
 SLF_R 0.00043 ± 0.00003 0.00041 ± 0.00003 0.00039 ± 0.00002 0.002* 0.124 0.001** 0.172
 SLFTP_L† 0.00042 ± 0.00004 0.00039 ± 0.00003 0.00037 ± 0.00002 0.007* 0.140 0.001** 0.118
 SLFTP_R 0.00042 ± 0.00003 0.00040 ± 0.00002 0.00037 ± 0.00002 0.002* 0.346 0.002** 0.080
 UF_L 0.00043 ± 0.00003 0.00042 ± 0.00003 0.00039 ± 0.00002 0.021* 0.859 0.020** 0.189
 UF_R 0.00044 ± 0.00003 0.00043 ± 0.00002 0.00041 ± 0.00002 0.013* 0.993 0.013** 0.104

Data are mean values ± standard deviation. *p < 0.05 in 3-group comparison, **p < 0.05 (parametric tests) or p < 0.017 (nonparametric tests) in post-hoc analysis, †Tested using nonparametric method. aP values for comparison among 3 groups, bP values for comparison between HAND and HIV-IC groups, cP values for comparison between HAND and HC groups, dP values comparison between HIV-IC and HC groups. ATR = anterior thalamic radiation, CCG = cingulum (cingulate gyrus), Ch = cingulum (hippocampus), CST = corticospinal tract, DTI = diffusion tensor imaging, FA = fractional anisotropy, FCPM = forceps major, FCPm = forceps minor, HC = healthy controls, IFOF = inferior fronto-occipital fasciculus, ILF = inferior longitudinal fasciculus, L = left, MD = mean diffusivity, R = right, RD = radial diffusivity, ROI = region-of-interest, SLF = superior longitudinal fasciculus, SLFTP = SLF temporal part, UF = uncinate fasciculus