Table 1.
Baseline patient and disease characteristics from 822 patients on E2805 for which adequate primary RCC tissue was available for analysis
| N (%) | ||
|---|---|---|
| Sex | Female | 289 (35.2) |
| Male | 533 (64.8) | |
| Age | ≤ 48 | 226 (27.5) |
| 49-56 | 220 (26.8) | |
| 57-64 | 186 (22.6) | |
| ≥ 65 | 190 (23.1) | |
| Histology | Clear Cell | 676 (82.2) |
| Chromophobe | 31 (3.8) | |
| Papillary | 64 (7.8) | |
| Other | 51 (6.2) | |
| Sarcomatoid features | No | 748 (91.0) |
| Yes | 73 (8.9) | |
| Missing | 1 (0.1) | |
| Fuhrman grade | 1/2 | 310 (37.7) |
| 3/4 | 512 (62.3) | |
| Path T-stage | 1 | 84 (10.2) |
| 2 | 236 (28.7) | |
| 3 | 491 (59.7) | |
| 4 | 11 (1.3) | |
| Path N-stage | 0 | 299 (36.4) |
| 1 | 37 (4.5) | |
| 2 | 23 (2.8) | |
| X | 463 (56.3) | |
| Arm | Sunitinib | 273 (33.2) |
| Sorafenib | 272 (33.1) | |
| Placebo | 277 (33.7) |