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. 2018 Jan 25;154(1):156–165. doi: 10.1111/imm.12882

Figure 3.

Figure 3

Incubation with hepatitis C virus (HCV) core protein increases signal transducer and activator of transcription 5 (STAT5) activation in CD8+ T‐cells. CD8+ T‐cells were incubated with or without HCV core protein (5 µg/ml) for 72 hr before treatment with interleukin‐7 (IL‐7; 1 ng/ml) for 15 min. Cells were then labelled with anti‐pSTAT5 antibody and analysed on a flow cytometer. (a) Representative histogram depicting effect of HCV core on STAT5 activation. (b) Mean MFI ± SD of pSTAT5 production (i.e. activated STAT5; two‐tailed paired Student's t‐test, n = 6).