Table 3.
Serum cytokine (pg/ml) (mean ± s.e.m.) | Healthy controls (n = 6) | Remission SLE (n = 6) | Active SLE (n = 6) | PRES/SLE (n = 14) |
---|---|---|---|---|
IL‐2 | 0·07 ± 0·04 | 0·08 ± 0·05 | 0·35 ± 0·27 | 0·43 ± 0·31 |
IL‐4 | 0·17 ± 0·15 | 0·23 ± 0·11 | 0·32 ± 0·27 | 0·36 ± 0·27 |
TNF‐α | 0·45 ± 0·37 | n.d. | 0·32 ± 0·32 | 0·35 ± 0·32 |
IFN‐γ | 0·08 ± 0·08 | 0·16 ± 0·15 | n.d. | 0·26 ± 0·15 |
VEGF | 653 ± 275 | 153 ± 62 | 223 ± 116 | 173 ± 66 |
Soluble CD40L | 3923 ± 1200 | 2724 ± 1296 | 1445 ± 1252 | 2620 ± 773 |
IL = interleukin; IFN = interferon; PRES = posterior reversible encephalopathy syndrome; s.e.m. = standard error of the mean; SLE = systemic lupus erythematosus; TNF = tumour necrosis factor; n.d. = not detected; VEGF = vascular endothelial growth factor.